Accelerated Growth of Mammary Tumor Cells in Normal and Athymic Mice after Treatment in Vitro with Dexamethasone1
نویسندگان
چکیده
The tumorigenicity of dexamethasone-treated tissuecultured mammary tumor cells was compared to that of untreated mammary tumor cells. The dexamethasone-induced cells progressed faster in normal syngeneic ani mals than did untreated mammary tumor cells. The fact that the growth rate differential was also observed in athymic mice suggests that T-lymphocyte-mediated im munity was not a factor in the accelerated progression in vivo of the tumor cells that had been cultured in the presence of dexamethasone.
منابع مشابه
Accelerated growth of mammary tumor cells in normal and athymic mice after treatment in vitro with dexamethasone.
The tumorigenicity of dexamethasone-treated tissue-cultured mammary tumor cells was compared to that of untreated mammary tumor cells. The dexamethasone-induced cells progressed faster in normal syngeneic animals than did untreated mammary tumor cells. The fact that the growth rate differential was also observed in athymic mice suggests that T-lymphocyte-mediated immunity was not a factor in t...
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